Two infiltrating T cell populations (CD8+CD69+CD103+ and CD8+CD69+CD103-) were isolated from 3 breast cancer tumors by FACS for gene expression profiliing. Unstranded RNA-seq were completed for 2 T ce
The cGAS-STING pathway plays a central role in controlling tumor progression through nucleic acid sensing and type I Interferon production. Here, we identify Poly(rC) Binding Protein 1 (PCBP1) as a tu
Innate and type 1 cell-mediated cytotoxic immunity function as important extracellular control mechanisms that maintain cellular homeostasis. Interleukin-12 (IL12) is an important cytokine that links