Genome-wide maps of SMAD3-binding sites in SW480 and their derivative cells.
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https://www.ncbi.nlm.nih.gov/sra/SRP131921
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资源简介：
We report that nuclear PTEN negatively regulates DNA-binding activity of SMAD3. We compared SMAD3 binding activity in colorectal tumor cells without or with a nuclear PTEN (C124S) mutant. Overall design: ChIP-seq analysis of SMAD3 binding activity in colorectal tumor cells SW480, SW480 with PTEN knockout (SW480 KOEMT), and PTEN-negatvie SW480 reconstituted with a nuclear PTEN (C124S) mutant (SW480 KOEMT + nuclear PTEN [C124S]).
创建时间：
2021-01-02
