Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB H11-E light chain

Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB H11-E light chain Descriptor: Fab H11-E heavy chain, Fab H11-E light chain, Insulin-degrading enzyme Authors: Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J. Deposit date: 2017-10-26 Release date: 2018-02-07 Last modified: 2024-11-20 Method: ELECTRON MICROSCOPY (7.2 Å) Cite: Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme. Elife, 7, 2018

人胰岛素降解酶（Insulin-degrading enzyme）与FAB H11-E重链、FAB H11-E轻链复合物的冷冻电镜（Cryo-EM）结构。描述：FAB H11-E重链、FAB H11-E轻链、人胰岛素降解酶（Insulin-degrading enzyme）。作者：Liang, W.G、Zhang, Z、Bailey, L.J、Kossiakoff, A.A、Tan, Y.Z、Wei, H、Carragher, B、Potter, S.C、Tang, W.J.。入库日期：2017-10-26。发布日期：2018-02-07。末次修改日期：2024-11-20。方法：电子显微镜（分辨率7.2 Å）。引用文献：《整合式冷冻电镜解析人胰岛素降解酶捕获并降解胰岛素的机制》，《Elife》，第7卷，2018年。