Effects of Crystalline Silica Inhalation in a High-Fat Western Diet
收藏ICPSR2025-01-01 更新2026-04-16 收录
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https://www.datalumos.org/datalumos/project/239401/version/V1/view
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资源简介：
Adipose tissue (AT), an endocrine organ, plays a central role in maintenance of whole-body energy homeostasis through its release of adipokines. Obesity, affecting over 40% of American adults, disrupts adipocyte metabolism leading to chronic systemic inflammation and metabolic dysfunction (MetDys). MetDys is associated with impaired lung function, pulmonary hypertension, and asthma. The aim of this study was to investigate the effects of silica inhalation in a pre-existing MetDys animal model to determine if an occupational exposure of silica dust has the potential to initiate or further the progression of MetDys associated conditions.
提供机构：
United States Department of Health and Human Services. Centers for Disease Control and Prevention. National Institute of Occupational Safety and Health
创建时间：
2025-01-01
