SAP30 promotes breast cancer progression and metastasis by gene activation (ATAC-Seq)
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https://www.ncbi.nlm.nih.gov/sra/SRP403953
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资源简介:
SAP30 recuits MLL1 to induce H3K4 trimethylation, increase chromatin accessobility and enhances Pol II binding on angiogenesis and migration genes to activate their expression, leading to breast cancer progression and metastasis Overall design: Parental and SAP30 KO MDA-MB-231 cells were subjected to ATAC-seq, and chromatin accessobility on subsets of genes were compared.
创建时间:
2023-09-15



