Association Analyses of APOB, B3GA4, LDLR, and PCSK9 genes.

Secondary traits, total cholesterol levels (TCL), high density lipoprotein (HDL), body mass index (BMI), diastolic blood pressure (DiasBP), systolic blood pressure (SysBP), triglyceride (TG) and insulin levels (INSULIN) were studied.aFor CMC, WSS, KBAC, and SKAT, variants with MAF≤1% were analyzed.bFor VT, variants with MAF≤5% were analyzed.cStatistical significance for all tests was obtained empirically via 5,000 permutations. Nominally significant p-values are labeled with an asterisk, while the associations that are significant after Bonferroni corrections are labeled with a pound sign.