The specific functional features of the epidermal keratinocytes are determined by the activity of many genes. The aim of the project was to characterize the role of HSPA2, a member of the HSPA chapero

NIAID Data Ecosystem60

Smad3 binding regions in differentiated human progenitor epidermal keratinocytes (HPEK).

TGF-β信号通路

皮肤生物学

Smad family proteins transduce signals downstream of transforming growth factor-beta (TGF-beta) and are one of the factors that regulate target genes related to diseases affecting the skin. We here id

NIAID Data Ecosystem40

Mediator 1 deficiency enhances epidermal cell fate and accelerates injury induced epidermal regeneration

皮肤生物学

再生医学

Cell fates are defined by specific transcriptional program. Previously, we developed a unique stem cell regeneration mouse model, in which transcriptional program for ectoderm organs such as tooth and

NIAID Data Ecosystem70

Comparison of gene expression in AhR WT (+/+) and AhR KO (-/-) primary mouse keratinocytes. Mus musculus

皮肤生物学

转录组调控

The AhR is a ligand activated transcription factor that may be important in normal skin physiology. We compared gene expression profiles between AhR Wt and AhR KO primary mouse keratinocyte cultures.

NIAID Data Ecosystem50