RLM Stability Data
收藏NIAID Data Ecosystem2026-05-01 收录
下载链接：
https://doi.org/10.7910/DVN/LCPHAZ
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资源简介：
Hepatic metabolic stability is a key pharmacokinetic parameter in drug discovery. Metabolic stability is usually assessed in microsomal fractions and only the best compounds progress in the drug discovery process. A high-throughput single time point substrate depletion method in rat liver microsomes (RLM) is employed at the National Center for Advancing Translational Sciences (NCATS) as a Tier 1 assay. This dataset has two files. First file (dataset_rlm_ncats.tab) contains 2528 compounds and the second file (drugs_rlm_ncats.tab) contains 220 approved drugs, both compound sets tested in the same RLM assay.
创建时间：
2023-07-31
