A robust human airway organoid platform enables scalable expansion and trajectory mapping of pulmonary neuroendocrine cells

This Zenodo repository contains single-cell RNA sequencing (scRNA-seq) datasets associated with the publications listed below. NEr-fAOs “A robust human airway organoid platform enables scalable expansion and trajectory mapping of pulmonary neuroendocrine cells” (Candeli et al., 2026) STARsolo.velocyto_NEr-fAOs.h5ad: Unprocessed AnnData (.h5ad) object used to run the analysis pipeline (https://github.com/daytonlab/NEr-fAOs_2026) NEr_fAOs_processed.zip: Processed gene expression matrices and corresponding metadata for reuse and downstream analyses. Human fetal lung primary tissue “In vitro and in vivo development of the human airway at single-cell resolution” (Miller et al., 2020) Conchola2023FetalEpithelium.zip: Processed gene expression matrices with updated metadata annotation (Conchola et al., 2023). CellTagged lung organoids “Regionally distinct progenitor cells in the lower airway give rise to neuroendocrine and multiciliated cells in the developing human lung” (Conchola et al., 2023) Conchola2023CellTagging.zip: Processed gene expression matrices and corresponding metadata.