Crystal structure of aspartate transcarbamoylase from Trypanosoma cruzi in complex with carbamoyl aspartate (CA) and phosphate (Pi)

Crystal structure of aspartate transcarbamoylase from Trypanosoma cruzi in complex with carbamoyl aspartate (CA) and phosphate (Pi) Descriptor: ASPARTIC ACID, Aspartate carbamoyltransferase, N-CARBAMOYL-L-ASPARTATE, ... Authors: Matoba, K, Shiba, T, Nara, T, Aoki, T, Nagasaki, S, Hayamizu, R, Honma, T, Tanaka, A, Inoue, M, Matsuoka, S, Balogun, E.O, Inaoka, D.K, Kita, K, Harada, S. Deposit date: 2019-03-04 Release date: 2020-03-04 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystallographic snapshots of Trypanosoma cruzi aspartate transcarbamoylase revealed an ordered Bi-Bi reaction mechanism To Be Published

克氏锥虫（Trypanosoma cruzi）来源的天冬氨酸转氨甲酰酶（aspartate transcarbamoylase）与氨甲酰天冬氨酸（carbamoyl aspartate, CA）及磷酸（phosphate, Pi）复合物的晶体结构。相关描述项包括：天冬氨酸（ASPARTIC ACID）、天冬氨酸转氨甲酰酶（Aspartate carbamoyltransferase）、N-氨甲酰-L-天冬氨酸（N-CARBAMOYL-L-ASPARTATE）等。作者：Matoba, K.、Shiba, T.、Nara, T.、Aoki, T.、Nagasaki, S.、Hayamizu, R.、Honma, T.、Tanaka, A.、Inoue, M.、Matsuoka, S.、Balogun, E.O.、Inaoka, D.K.、Kita, K.、Harada, S.。提交日期：2019-03-04；发布日期：2020-03-04；最后修改日期：2023-11-22。实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.4 Å。引用信息：《克氏锥虫天冬氨酸转氨甲酰酶的晶体快照揭示有序Bi-Bi反应机制》（Crystallographic snapshots of Trypanosoma cruzi aspartate transcarbamoylase revealed an ordered Bi-Bi reaction mechanism），待发表。