Next generation monomeric IgG4 Fc
收藏Protein Data Bank Japan2024-10-16 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6wna
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Next generation monomeric IgG4 Fc Descriptor: Beta-2-microglobulin, IgG receptor FcRn large subunit p51, Immunoglobulin heavy constant gamma 4, ... Authors: Oganesyan, V.Y, Shan, L, van Dyk, N, Dall'Acqua, W.F. Deposit date: 2020-04-22 Release date: 2021-09-15 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.4 Å) Cite: In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance. Commun Biol, 4, 2021
下一代单体IgG4 Fc描述数据集:β2-微球蛋白(Beta-2-microglobulin)、IgG受体FcRn大亚基p51(IgG receptor FcRn large subunit p51)、免疫球蛋白γ4恒定区重链(Immunoglobulin heavy constant gamma 4)……
作者:Oganesyan, V.Y.、Shan, L、van Dyk, N、Dall'Acqua, W.F.
存入日期:2020-04-22
发布日期:2021-09-15
最后修改日期:2024-10-16
研究方法:X射线衍射法(2.4埃)
引用文献:《通过结构指导实现单体Fc与单价双特异性设计的体内药代动力学增强》,发表于《通讯生物学(Commun Biol)》,2021年,第4卷
创建时间:
2020-04-22



