Data supporting the article: HSPA6 orchestrates EV71 virulence by serving as a molecular chaperone that stabilizes the VP1-SCARB2 uncoating complex

This repository contains the raw data and supplementary materials supporting the manuscript titled "HSPA6 orchestrates EV71 virulence by serving as a molecular chaperone that stabilizes the VP1-SCARB2 uncoating complex". The provided datasets are made available in accordance with the journal's Open Data policy to facilitate transparency and reproducibility. Contents of the repository: This dataset is organized into the following sub-folders: (1) Western Blot (WB) Raw Images: Includes original, uncropped Western blot membranes used in Figure [1, 2, 4, 5, 6, S1, S3]. File formats: .tif Annotations: Bands are labeled corresponding to the protein targets and experimental conditions described in the manuscript. (2) Immunofluorescence (IF) Microscopy: Original confocal microscopy images demonstrating the colocalization of HSPA6, EV71 VP1 and SCARB2 proteins. File formats: .tif (3) Quantitative Data (Figure Source Data): Excel spreadsheets (.xlsx) containing raw numerical data for all bar charts and quantification figures (e.g., relative expression, viral titers) and processed transcriptomic analysis data (e.g., DEGs) utilized in Figure 3. Data Usage: These data are licensed under the Creative Commons Attribution 4.0 International (CC-BY 4.0) license. Please cite this dataset and the associated manuscript when using these data. Contact Information: For any inquiries regarding the datasets or methods during the review process, please contact the corresponding author: Qinchang Zhu College of Pharmacy, Shenzhen Technology University E-Mail: [e-mail]