N6-methyladenosine regulates metabolic remodeling in kidney aging through transcription regulator GLIS1. N6-methyladenosine regulates metabolic remodeling in kidney aging through transcription regulator GLIS1

Aged-related kidney impairment that involves tubular epithelial cell senescence and renal fibrosis become a severe threaten for worldwide public health. m6A-mRNA epitranscriptomic microarray was performed to reveal the targeted genes with abnormal m6A modification in aged human kidney tissues. Overall design: Control group and experimental group,Biological replicates: 3control replicates, 3 experimental replicates.