Ovarian Cancer

When patients see their GPs with symptoms that might indicate ovarian cancer, a CA125 blood test is carried out but this test does not identify all patients with ovarian cancer and wrongly identifies some patients as at risk of having ovarian cancer. It is possible that this can be improved by carrying out an additional test, HE4, on the same blood sample and calculating a score called the ROMA score: this is being investigated in the SONATA study with the aim of improving ovarian cancer diagnosis.