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Genomic landscape of somatic alterations in esophageal squamous cell carcinoma and gastric cancer

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NIAID Data Ecosystem2026-03-09 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE43470
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Gastric cancer and esophageal cancer are the 2nd and 6th leading causes of cancer death worldwide. We analyzed DNA copy numbers for 73 ESCC (43 SNP5.0 and 30 500K SNP) with the Affymetrix SNP arrays . Our analyses implicated potential driver mutations involving the following genes: mutations in TP53, BRCA2, NOTCH2, CTNNB1, and LEPREL2; amplification of CCND1, FGF3/4/19, and MYC; and deletion of CDKN2A/B. Copy number analysis of Affymetrix SNP5.0 arrays
创建时间:
2016-05-09
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