X-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) in a ternary complex with U0126, ADP and MG2P

X-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) in a ternary complex with U0126, ADP and MG2P Descriptor: (2Z)-bis{amino[(2-aminophenyl)sulfanyl]methylidene}butanedinitrile, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... Authors: Fischmann, T.O. Deposit date: 2008-09-30 Release date: 2009-02-24 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal Structures of MEK1 Binary and Ternary Complexes with Nucleotides and Inhibitors. Biochemistry, 48, 2009

人类丝裂原活化蛋白激酶激酶1（MEK1）与U0126、二磷酸腺苷（ADP）及MG2P形成三元复合物的X射线晶体结构。结构描述符：(2Z)-双{氨基[(2-氨基苯基)硫基]亚甲基}丁二腈、腺苷-5'-二磷酸、钙离子……作者：菲施曼（Fischmann, T.O.）；提交日期：2008-09-30；发布日期：2009-02-24；最后修改日期：2024-02-21；测试方法：X射线衍射（分辨率2 Å）；引用文献：《与核苷酸及抑制剂结合的MEK1二元与三元复合物晶体结构》，《生物化学》（Biochemistry），第48卷，2009年。