Additional file 4 of FT-GPI, a highly sensitive and accurate predictor of GPI-anchored proteins, reveals the composition and evolution of the GPI proteome in Plasmodium species

Additional file 4: Table S4. Description of proteins from the GPI-AP reference sets. A. P. falciparum reference set from Gilson, et al. [17]. Protein size, number of TM and signal 4.0 prediction were recovered from PlasmoDB. SignalP 5.0 and PredGPI were performed online [47,52]. Essential genes were described by a Mutation Index Score (MIS) and Fitness score (MFS) from transposon saturation mutagenesis experiments [77]. Sequences were downloaded from PlasmoDB release 51. B. P. vivax reference set from Carlton et al [38]. The list of GPI-APs was given in Suppl. Table 8 of the P. vivax genome paper. Sequence analysis was performed as in (A). No information was available concerning gene essentialness in P. vivax. Negative predictions are in red. * Some proteins had no gene names and were arbitrarily labelled from gpi1 to gpi4. P. falciparum Pf_gpi1 P. vivax ortholog was absent from Carlton et al list [38]. P. falciparum P36 ortholog was not in Gilson et al list [17]. The gpi3 protein was labelled as P32 in some references.