CROFT-Seq raw sequencing data

NIAID Data Ecosystem2026-05-10 收录

CRISPR脱靶检测

深度测序

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP530349 数据链接链接失效反馈

官方服务：

资源简介：

Deep sequencing results for off-target detection of CRISPR-Cas9 nuclease in vitro with CROFT-Seq.

创建时间：

2026-02-11

Metadata for pooled faecal samples used in deep sequencing

元数据

深度测序

This dataset contains metadata for pooled faecal samples used in the deep sequencing component of the study. Samples from gorillas and humans were pooled in groups of 20, with a few exceptions. Livest

Figshare2025-08-01 更新80

PEAC-seq: an unbiased in vivo CRISPR off-target detection technique

CRISPR脱靶检测

基因编辑安全性

Development of PEAC-seq for unbiased off-target detection and translocation According to the screen and the tag insertion test, we attached a 21nt cytosine-depleted template to the 3’ of pegRNA. We re

NIAID Data Ecosystem70

Number of GUIDE-seq datasets and identified digested sequences. The numbers in the parentheses include technical replicates.

CRISPR脱靶检测

基因编辑序列分析

Number of GUIDE-seq datasets and identified digested sequences. The numbers in the parentheses include technical replicates.

Figshare2025-07-18 更新60

Additional file 10: of NmeCas9 is an intrinsically high-fidelity genome-editing platform

基因编辑

深度测序

Table S3. Targeted deep sequencing read count data for all sgRNAs used and for all off-targets detected by GUIDE-seq. (XLSX 44 kb)

DataCite Commons2024-02-08 更新70

IDLV capture for gRNA off-target analysis

CRISPR脱靶检测

基因编辑安全性

Vector capturing was used for experimental identification of potential off-target sites of 2 gRNA targeting alpha globin genes Overall design: K562 cells were transduced with an Integrase-defective l

NIAID Data Ecosystem60

CROFT-Seq raw sequencing data

资源简介：

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