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ChIP-chip data of Rrm3-Flag in wild-type and rpb1-1 cells

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE55184
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Transcription is a major contributor to genome instability.A main cause of transcription-associated instability relies on the capacity of transcription to stall replication. Such genome instability is increased in RNAPII mutants. ChIP-chips performed in asynchronous cultures showed an increase of the Rrm3 binding signal all over the genome in rpb1-1 compared to wild-type. ChIP-chip studies were perfomed with antibody against Flag-tagged Rrm3 protein in both wild-type and rpb1-1 cells.
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2016-01-09
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