Crystal structure of human DIMETHYLARGININE DIMETHYLAMINOHYDROLASE-1 (DDAH-1) covalently bound with N5-(1-iminopentyl)-L-ornithine

Crystal structure of human DIMETHYLARGININE DIMETHYLAMINOHYDROLASE-1 (DDAH-1) covalently bound with N5-(1-iminopentyl)-L-ornithine Descriptor: N(G),N(G)-dimethylarginine dimethylaminohydrolase 1, N~5~-[(1S)-1-aminopentyl]-L-ornithine Authors: Lluis, M, Wang, Y, Monzingo, A.F, Fast, W, Robertus, J.D. Deposit date: 2010-10-13 Release date: 2010-11-10 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.4946 Å) Cite: Characterization of C-Alkyl Amidines as Bioavailable Covalent Reversible Inhibitors of Human DDAH-1. Chemmedchem, 6, 2011

人源二甲基精氨酸二甲基氨基水解酶-1（DDAH-1）与N⁵-(1-亚氨基戊基)-L-鸟氨酸共价结合的晶体结构。描述参数：N(G),N(G)-二甲基精氨酸二甲基氨基水解酶1，N⁵-[(1S)-1-氨基戊基]-L-鸟氨酸。作者：Lluis M、Wang Y、Monzingo A.F、Fast W、Robertus J.D。提交日期：2010-10-13，发布日期：2010-11-10，最后修改日期：2024-11-20。实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.4946埃。引用文献：《C-烷基脒类化合物作为人源DDAH-1的可生物利用共价可逆抑制剂的表征》，发表于《ChemMedChem》2011年第6卷。