Transcriptomic analysis of embryonic hearts with conditional deletion of Wt1
收藏Alliance of Genome Resources2026-08-01 收录
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We performed a conditional ablation of Wt1 in the myocardium of mice embryos. RNASeq analysis identified differential expression of 137 genes in the E13.5 mutant heart as compared to controls. GO functional enrichment analysis suggested that both calcium ion regulation and modulation of potassium channels are deeply altered in the mutant myocardium mRNA profiles of E13.5 wild type (WT) and TnnT2Cre;Wt1flox mutant embryos
