Residue-centric rate of sequence evolution according to Rate4Site on orthogroups of 14 fungal species

Overall, 42 descriptors (features) are mapped on 2129854 residues comprising 3797 unique proteins.The legend for each descriptor is given in the associated header file.<br><br>Columns 1-4 provide protein identifiers:<br>- SGD identifier,<br>- ORF,<br>- UniprotKB,<br>- PDB code and chain of closest structure<br><br>Columns 5-8 correspond to the length in number of residues for each of the previously defined identifiers:<br>Columns 9-12 contain the residue number of each aligned position within the full sequence.<br><br>Columns 13-14 contain the residue name of each aligned position in respectively the sequence and the structure.<br><br>Columns 15-16 indicates whether aligned position correspond to a gap (indel) position in the sequence and the structure.<br><br>Columns 17-20 indicates whether the protein has disorder predictions from IUPRED or D2P2, evolutionary rate from Rate4Site and a PDB structure matching the protein.<br><br>Columns 21-24 contain the raw and normalized evolutionary rates at each position as well as the min. and max. evolutionary rate in the proteins (from raw values).<br><br>Columns 25-31 correspond to the information relevant to the PDB structure:- Identity % <br>- Overlap %<br>- Resolution<br>- Number of PDB matched<br>- Number of subunits in closest structure<br>- QSBIO error probability on quaternary structure assignment<br><br>Columns 32-36 correspond to the geometric descriptor which indicate whether the residue is:<br>- surface exposed<br>- buried<br>- at the interface<br>- relative Accessible Surface Area in monomeric form<br>-relative Accessible Surface Area in Biological UnitColumn 37-42 are indicating the various biophysical features mapped to the residue:<br>- predicted disordered by IUPRED<br>- predicted NOT disordered by IUPRED<br>- predicted disordered by D2P2<br>- predicted NOT disordered by D2P2<br>- predicted to be in PFAM or SUPERFAMILY domain<br>- predicted NOT to be in PFAM or SUPERFAMILY domain<br>