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Functionalization of Monofluoroallene and the Synthesis of Aryl-Substituted Conjugated Fluorodienes

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https://figshare.com/articles/dataset/Functionalization_of_Monofluoroallene_and_the_Synthesis_of_Aryl-Substituted_Conjugated_Fluorodienes/3743226
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4-Fluoroallenol 3a, prepared from 1, cyclized easily to 4 but preserved its fluoroallenyl integrity under oxidation and SN2 displacement to yield aldehyde, amine, mesylate, and halide 6. Allylic isomerization yielded 2-halo-1-fluoro-1,3-butadiene 7, which underwent a Suzuki coupling to give aryl-substituted conjugated diene 8.
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2016-08-20
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