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Shp2 Signaling Suppresses Senescence in PyMT-induced Mammary Gland Cancer in Mice [Mouse430_2 array]

ChEBI2015-03-06 更新2026-07-21 收录

乳腺肿瘤模型

细胞衰老调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-50517 数据链接链接失效反馈

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资源简介：

Shp2 Signaling Suppresses Senescence in PyMT-induced Mammary Gland Cancer in Mice [Mouse430_2 array]

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创建时间：

2015-03-06

细胞恶性转化

细胞衰老调控

During oncogenic transformation, cells acquire genetic mutations that override the normal mechanisms regulating cellular proliferation. Excessive expression of activating transcription factor 4 (ATF4)

NIAID Data Ecosystem50

Androgen Receptor Drives Cellular Senescence

前列腺癌分子机制

细胞衰老调控

The accepted androgen receptor (AR) role is to promote proliferation and survival of prostate epithelium and thus prostate cancer progression. While growth-inhibitory, tumor-suppressive AR effects hav

Figshare2016-01-18 更新30

Loss of Nuclear Receptor Nr4a3 Alleviates Cellular Senescence to Promote Adult Direct Cardiac Reprogramming (CUT&Tag)

器官再生医学

细胞衰老调控

Direct cardiac reprogramming of fibroblast to cardiomyocytes represents a potential means of restoring cardiac function following injury. However, aged and adult fibroblast are less efficient for repr

NIAID Data Ecosystem30

Densely Ionizing Radiation Effects on the Microenvironment Promote Aggressive Trp53 Null Mammary Carcinomas. Mus musculus

辐射致癌风险

乳腺肿瘤模型

Densely ionizing radiation is a major component of the space radiation environment and has potentially greater carcinogenic effect compared to sparsely ionizing radiation that is prevalent in the terr

NIAID Data Ecosystem40

DNA methylation protects cancer cells against senescence

癌症表观遗传学

细胞衰老调控

These data have been processed by Cell Ranger (v8.0, 10X Genomics). Samples: HCT116 WT, HCT116 UHRF1-AID1 cells, HCT116 DNMT1-AID1 cells, HCT116 UHRF1-AID1/DNMT1-AID1 cells. Treatment: All cells wer

Zenodo2025-05-20 更新30

Shp2 Signaling Suppresses Senescence in PyMT-induced Mammary Gland Cancer in Mice [Mouse430_2 array]

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