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Sculpting humoral immunity through dengue vaccination to enhance protective immunity.

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Previously characterized monoclonal antibodies were tested for reactivity against wild-type and mutant DENV1 VLPs. Mutation at K310 caused a greater than 90% reduction in reactivities compared to wild-type, suggesting that these are critical residues in binding.

提供机构:
IEDB
创建时间:
2012-01-01
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