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Human KRAS G12D (GDP-bound) in complex with macrocyclic peptide inhibitor AP4959

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Protein Data Bank Japan2026-07-01 更新2026-07-20 收录
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Human KRAS G12D (GDP-bound) in complex with macrocyclic peptide inhibitor AP4959 Descriptor: 1,2-ETHANEDIOL, AP4959, GUANOSINE-5'-DIPHOSPHATE, ... Authors: Yamano, T, Chiyoda, A, Fukami, T.A, Tanada, M, Irie, M, Torizawa, T. Deposit date: 2026-03-04 Release date: 2026-05-27 Last modified: 2026-07-01 Method: X-RAY DIFFRACTION (2.53 Å) Cite: Structure-Activity Relationship Analysis of Macrocyclic Peptide RAS Inhibitors: Spotlight on the Solvent-Exposed Region. Acs Med.Chem.Lett., 17, 2026

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2026-03-04
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