Supporting data for “Perturbations in the Frequency and Function of Exhausted and Classical Memory B cells – Role in Systemic lupus Erythematosus and Lupus Nephritis”

This dataset indicates that alterations in the number and function of classical and exhausted memory B cells may be associated with the risk of lupus nephritis (LN) relapse. Additionally, genetic dysregulations in exhausted and classical memory B cells can affect their homeostasis, thereby influencing the development of autoimmune diseases such as systemic lupus erythematosus (SLE) and LN.

本数据集表明，经典和耗竭记忆B细胞的数量和功能变化可能与狼疮性肾炎（LN）复发的风险相关。此外，耗竭和经典记忆B细胞的遗传失调可能影响其稳态，从而影响自身免疫性疾病，如系统性红斑狼疮（SLE）和LN的发展。