The STRIPAK complex regulates response to chemotherapy through p21 and p27
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE145618
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资源简介：
We report that loss of a component of the STRIPAK complex in MDA-MB-231 cells known as STRIP1 causes cell cycle arrest and decreased proliferation due to increased expression of cyclin dependent kinase inhibitors, p21 and p27. This change in p21 and p27 expression results in a subset of cells forgoing therapy-induced senescence and becoming proliferative. Examination of the varying RNA levels in control MDA-MB-231 cells versus STRIP1-depleted cells
创建时间：
2020-04-10
