Characterization of mature Tregs in the thymus. Characterization of mature Tregs in the thymus

Using Foxp3.RFP Rag.GFP reporter mice, mature Tregs in the thymus were characterized by performing RNA sequencing on Rag.GFP– and Rag.GFP+ Tregs that were isolated from the thymus and Tregs isolated from the spleen Overall design: mRNA profiles of Rag.GFP- (mature)Tregs from thymus, Rag.GFP+(recently developed) Tregs from thymus and Tregs from spleen were generated by MARSeq Method