Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Bacillus anthracis in the complex with a product IMP and the inhibitor P182
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Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Bacillus anthracis in the complex with a product IMP and the inhibitor P182 Descriptor: GLYCEROL, INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase, ... Authors: Kim, Y, Maltseva, N, Mulligan, R, Makowska-Grzyska, M, Gu, M, Gollapalli, D, Hedstrom, L, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2017-02-17 Release date: 2017-03-01 Last modified: 2026-03-25 Method: X-RAY DIFFRACTION (2.75 Å) Cite: The Enzymatic Activity of Inosine 5'-Monophosphate Dehydrogenase May Not Be a Vulnerable Target for Staphylococcus aureus Infections. Acs Infect Dis., 7, 2021
炭疽芽孢杆菌来源的次黄嘌呤核苷酸脱氢酶（Inosine Monophosphate Dehydrogenase）催化结构域与产物次黄嘌呤单核苷酸（IMP，Inosine Monophosphate）及抑制剂P182形成复合物的晶体结构
描述组分：甘油、肌苷酸、次黄嘌呤-5'-单核苷酸脱氢酶……
作者：Kim Y、Maltseva N、Mulligan R、Makowska-Grzyska M、Gu M、Gollapalli D、Hedstrom L、Anderson W.F.、Joachimiak A，传染病结构基因组学中心（Center for Structural Genomics of Infectious Diseases, CSGID）
提交日期：2017-02-17
发布日期：2017-03-01
最后更新：2026-03-25
实验方法：X射线衍射（分辨率2.75埃）
引用文献：《次黄嘌呤-5'-单核苷酸脱氢酶的酶活或并非金黄色葡萄球菌感染的易感靶点》，ACS Infectious Diseases，7卷，2021年
创建时间：
2017-02-17
