In Vivo Mutagenesis of a Ketosynthase Domain Uncovers Productivity and Specificity Control in Modular Polyketide Synthases
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AlphaFold3 Beta–predicted KS5 domain models of variant 30 (Model 1 shown in the main text). AlphaFold3 Beta–predicted wild-type KS5 domain models (Model 1 shown in the main text). Distance matrix of selected KS domain sequences. qNMR data of fermentation extracts from Streptomyces cinnamonensis A495-WT and KR40-1 variants.
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2025-09-24



