Intercellular Adhesion Molecule 1-Positive Dental Pulp Stem Cells

Objectives: Dental pulp stem cells are crucial in immune response regulation. However, sub-clusters of these cells involved in deep caries progression remain unidentified. This study explores the role of Intercellular adhesion molecule 1-positive dental pulp stem cells (ICAM1+DPSCs) within the immune microenvironment of dental pulp tissue affected by deep caries, aiming to establish a theoretical foundation and novel strategies for its prevention and treatment.Methods: Use flow cytometry to sort ICAM1+ DPSCs and ICAM1- DPSCs for RNA-seq. Overall design: Use flow cytometry to sort human dental pulp stem cells into ICAM1+ DPSCs and ICAM1- DPSCs for RNA-seq.