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Ciprofloxacin resistance in Salmonella Dublin

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NIAID Data Ecosystem2026-05-10 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP648872
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This study investigated ciprofloxacin resistance among biobanked Salmonella isolates collected from 1985 to 2023 by the Biomedical Research Laboratory at Oregon State University. A Salmonella Dublin isolated in 2023 was found to be ciprofloxacin-resistant (MIC 1.5 ug/ml) and also harbored an Asparagine (N) to Serine (S) mutation at position 868 in the GyrA protein. Compared to its ciprofloxacin-sensitive Salmonella Dublin counterpart, this resistant isolate markedly expressed the acrA, acrB, ramA, and soxS genes.
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2026-01-19
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