Identification of Aurora B pathway involved in the anti-cancer effects by Paeoniae Radix extracts based on whole transcriptome analysis

we profiled the change in genome-wide gene expression of human lung cancer cells in response to treatment of water and ethanol extracts of PR and its ingredients in a dose dependent manner to investigate PR efficacy at the molecular pathway level. Total whole transcritome profiles treated with water extract of Paeoniae Radix (PR), ethanol extract of PR, and eight ingredients in A 549 lung cancer cell lines.