Sequences of sgRNAs used to make isogenic knock-out and ATRX MEDs.

Figshare2023-08-04 更新2026-04-28 收录

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https://figshare.com/articles/dataset/Sequences_of_sgRNAs_used_to_make_isogenic_knock-out_and_ATRX_MEDs_/23871502 数据链接链接失效反馈

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The guide efficiency is shown as predicted by the CRISPOR design tool. (XLSX)

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2023-08-04

Crystal structure of xCas9 P411T

蛋白质晶体结构解析

CRISPR-Cas9基因编辑

Crystal structure of xCas9 P411T Descriptor: CRISPR-associated endonuclease Cas9/Csn1 Authors: Bao, R, Liu, H.Y, Luo, Y.Z, Song, Y.J. Deposit date: 2021-09-29 Release date: 2022-04-06 Last modified: 2

Protein Data Bank Japan2023-11-29 更新50

Single-cell transcriptomes and runx2b-/- mutants reveal the genetic signatures of intermuscular bone formation in teleosts

鱼类肌间骨遗传机制

CRISPR-Cas9基因编辑

Purpose: Intermuscular bones (IBs) are hard spicules, mainly existing in the myosepta of recent vertebrates. This evolutionary trait has puzzled biologists and consumers, and the molecular basis of IB

NIAID Data Ecosystem40

DataSheet2_Whole genome sequencing of CCR5 CRISPR-Cas9-edited Mauritian cynomolgus macaque blastomeres reveals large-scale deletions and off-target edits.xlsx

CRISPR-Cas9基因编辑

非人灵长类基因组学

Introduction: Genome editing by CRISPR-Cas9 approaches offers promise for introducing or correcting disease-associated mutations for research and clinical applications. Nonhuman primates are physiolog

NIAID Data Ecosystem20

Genome-wide precomputed Pythia predictions for CRISPR-Cas9 3′-tagging — Xenopus tropicalis

CRISPR-Cas9基因编辑

蛋白质标记设计

Pythia is a tool for designing CRISPR-Cas9 knock-in strategies for endogenous C-terminal protein tagging, which ranks candidate sgRNA/repair-template combinations based on predicted editing outcomes.

Zenodo2026-04-25 更新40

Decorating chromatin for enhanced genome editing using CRISPR-Cas9

CRISPR-Cas9基因编辑

同源定向修复

To improve the efficiency of homology-directed repair of double-stranded breaks introduced by CRISPR-Cas9, a Cas9-PRDM9 (PR/SET Domain 9) fusion protein was generated and tested in HEK-293T cells. RNA

NIAID Data Ecosystem20

Sequences of sgRNAs used to make isogenic knock-out and ATRX MEDs.

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