Shared αβ T Cell Receptor Usage in Lungs of Sarcoidosis Patients with Löfgren’s Syndrome [ePCR]
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE100556
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资源简介：
Expansions of CD4+ T cells utilizing TRAV12-1/TRBV2 were found exclusively in HLA-DR3+ LS patients. These TCRs shared CDR3 homology, suggesting that these T cells are responsible for recognizing sarcoidosis-associated antigen(s) and are involved in the local alveolitis. Analysis of TCR sequences from 12 sarcoidosis and 3 control patient blood and/or lung samples.
创建时间：
2021-07-25
