Spatio-temporal specific gene expression analysis in embryonic growth plate chondrocytes

The purpose of this study is to comprehensively analyze the developmental stages and spatially specific gene expression in the growth plate chondrocytes in femoral cartilage tissue during embryonic development. A series of analyses will identify spatiotemporally expressed membrane proteins in the tissue. Furthermore, the analysis will elucidate intracellular signals that are activated by their stimulation. We furthere aim to identify the way to artificially regulate physiological functions based on the molecular mechanisms elucidated.