Candidate SNPs in SLC8A1 significantly associated with DSBP120 (A), and LD r2 pattern between the best associated SNP (rs434082) and the other SNPs (B).

(A) Data generated by Plink assuming an additive genetic model. Permutation was performed and maintained the same robustness of significance. Effect sizes are on the mmHg scale (±s.e.) (except for PNat120, µEq/mmHg/minute) for increasing copy of the risk allele as estimated by the beta coefficient in linear regression.Position on chromosome 2 refers to 37.1 Genome Build of GRCh37 (http://www.ncbi.nlm.nih.gov/SNP).(B) #Linkage Disequilibrium between rs434082 and other SNP associated with ΔSBP120 trait.