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Effect of selective glucocorticoid receptor modulation (SGRM) on gene expression in human prostate cancer cell lines

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NIAID Data Ecosystem2026-05-01 收录
下载链接:
https://www.ncbi.nlm.nih.gov/sra/SRP102707
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资源简介:
Human prostate cancer cell lines treated with androgen receptor (AR) agonists/antagonists and concurrent glucocorticoid receptor (GR) agonist/antagonists Overall design: Human prostate cancer cell lines in charcoal-stripped FCS-containing media were treated for 3 days with AR agonists (R1881 1nM) +/-antagonist (enzalutamide 10uM) and then pulsed with 2 or 6 hour treatment with GR agonist (Dex 100nM) +/- antagonist (SGRM, 335 1uM and 297 1uM) after which RNA was collected and sequenced
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2024-04-18
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