Significant cortical thickness differences in the ROIs between HCs, IBS and UC subjects with and without controlling for anxiety and depression scores.

R: right; L: left; lOFG: lateral orbitofrontal gyrus; mOFG: medial orbitofrontal gyrus; Post: postcentral gyrus; aINS: aINSula; mINS: mid insula; pINS: posterior insula; aMCC: anterior mid cingulate cortex; pMCC: posterior mid cingulate cortex; pgACC: pregenual anterior cingulate cortex; sgACC: subgenual anterior cingulate cortex; q value: p value after FDR corrected at 5%, q value <.05 was considered significant; F(A): F score after controlling for anxiety; q(A): corrected p value after controlling for anxiety; F(D): F score after controlling for depression; q(D): corrected p value after controlling for depression.