Crystal structure of NFIC homodimer bound to DNA

Crystal structure of NFIC homodimer bound to DNA Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*AP*AP*GP*TP*TP*GP*GP*CP*AP*CP*CP*GP*TP*GP*CP*CP*AP*AP*CP*TP*T)-3'), DNA (5'-D(*AP*AP*GP*TP*TP*GP*GP*CP*AP*CP*GP*GP*TP*GP*CP*CP*AP*AP*CP*TP*T)-3'), ... Authors: Pan, S.L, Min, J.R, Liu, K. Deposit date: 2025-11-26 Release date: 2025-12-31 Last modified: 2026-07-01 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Biochemical and structural studies of NFIA and NFIC reveal a conserved mechanism for specific DNA recognition and provide insight into potential pathogenicity of disease-associated mutations. Acta Biochim.Biophys.Sin., 58, 2025