Beta cell dysfunction and identity loss induced by low dose of Interleukin-1β is associated with changes in histone acetylation and gene expression [RNA-seq]
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE110690
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We report maturity loss and dysfunction of primary mouse islets exposed to prolonged low Interleukin-1B exposure is associated with a decreassed expresion of key beta cell genes and a decreased H3K27ac mark Examination of mRNA profile of primary mouse islets exposed or non-exposed to Interleukin-1B for 10 days
创建时间:
2019-08-07



