Otulin

ENCODES a protein that exhibits cysteine-type deubiquitinase activity (ortholog); cysteine-type peptidase activity (ortholog); INVOLVED IN innate immune response (ortholog); negative regulation of inflammatory response (ortholog); negative regulation of NF-kappaB transcription factor activity (ortholog); ASSOCIATED WITH autosomal dominant craniometaphyseal dysplasia (ortholog); chondrocalcinosis (ortholog); Chondrocalcinosis 2 (ortholog); FOUND IN cytoplasm (ortholog); LUBAC complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; bisphenol A

编码一种表现出半胱氨酸型去泛素化酶活性（同源）；半胱氨酸型肽酶活性（同源）；参与先天免疫反应（同源）；炎症反应的负调控（同源）；NF-κB转录因子活性的负调控（同源）；与常染色体显性颅骨代谢性发育不良（同源）相关；软骨钙化（同源）；软骨钙化2（同源）；存在于细胞质中（同源）；LUBAC复合物（同源）；与2,3,7,8-四氯二苯并-对-二恶英；丙烯酰胺；双酚A相互作用。