Crystal structure of [Fe]-hydrogenase (Hmd) from Methanococcus aeolicus in complex with FeGP cofactor and methenyl-tetrahydromethanopterin (close form B)

Crystal structure of [Fe]-hydrogenase (Hmd) from Methanococcus aeolicus in complex with FeGP cofactor and methenyl-tetrahydromethanopterin (close form B) Descriptor: 1-{4-[(6S,6aR,7R)-3-amino-6,7-dimethyl-1-oxo-1,2,5,6,6a,7-hexahydro-8H-imidazo[1,5-f]pteridin-10-ium-8-yl]phenyl}-1-deoxy-5-O-{5-O-[(S)-{[(1S)-1,3-dicarboxypropyl]oxy}(hydroxy)phosphoryl]-alpha-D-ribofuranosyl}-D-ribitol, 5,10-methenyltetrahydromethanopterin hydrogenase, CHLORIDE ION, ... Authors: Huang, G, Wagner, T, Wodrich, M.D, Ataka, K, Bill, E, Ermler, U, Hu, X, Shima, S. Deposit date: 2018-08-07 Release date: 2019-08-28 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.85 Å) Cite: The atomic-resolution crystal structure of activated [Fe]-hydrogenase Nat Catal, 2019

嗜酸产甲烷球菌（Methanococcus aeolicus）来源的[Fe]-氢化酶（[Fe]-hydrogenase, Hmd）与FeGP辅酶（FeGP cofactor以及5,10-亚甲基四氢甲烷蝶呤（methenyl-tetrahydromethanopterin，闭式B）的复合物晶体结构。描述符：1-{4-[(6S,6aR,7R)-3-氨基-6,7-二甲基-1-氧代-1,2,5,6,6a,7-六氢-8H-咪唑并[1,5-f]蝶啶-10-鎓-8-基]苯基}-1-脱氧-5-O-{5-O-[(S)-{[(1S)-1,3-二羧基丙基]氧基}(羟基)磷酰基]-α-D-呋喃核糖基}-D-核糖醇，5,10-亚甲基四氢甲烷蝶呤氢化酶，氯离子（CHLORIDE ION），…… 作者：Huang, G, Wagner, T, Wodrich, M.D, Ataka, K, Bill, E, Ermler, U, Hu, X, Shima, S。提交日期：2018-08-07 发布日期：2019-08-28 最后修改日期：2024-01-17 实验方法：X射线衍射（X-RAY DIFFRACTION，分辨率1.85埃（1.85 Å）。引用：活化[Fe]-氢化酶的原子分辨率晶体结构，《自然·催化（Nat Catal）》，2019