five

Transcriptome-wide analysis of TRIM21-mediated changes in gene expression after challenge with virus and antibody

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE119119
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We report that TRIM21 plays a crucial role in mediating antibody interference of adenovirus gene delivery and simultaneously initiates a transcriptional programme of immune genes. Transcriptional changes in the liver of WT and TRIM21 KO animals 4h after injection with PBS (control samples), Ad5, Ad5 + rh9C12-WT or Ad5+rh9C12-H433A. 4 replicates per condition; 32 samples in total.
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2019-03-19
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