scRNA-seq and genomic reference of PBMC upon TNF Inhibitor Response in Ankylosing Spondylitis
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE277791
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The study identifies allograft inflammatory factor-1 (AIF-1) as a key marker of interferon (IFN) signature, which differentiates TNF inhibitor (TNFi) responders from non-responders in ankylosing spondylitis (AS) Peripheral blood mononuclear cells from AS patients were subjected to single-cell RNA sequencing to investigate differential gene expression, focusing on AIF-1 and IFN-related genes between TNFi responders and non-responders.
创建时间:
2025-05-03



