Prevalence of immunoglobulin G antibodies reacting with Simian Virus 40 (SV40) viral protein (VP) mimotopes in serum samples of patients affected by MS, OIND, NIND and HS∧.

∧Human sera were from patients affected by multiple sclerosis (MS), other inflammatory neurologic diseases (OIND), non-inflammatory neurologic diseases (NIND) and healthy subjects (HS1), (HS2).*The prevalence of SV40 antibodies in MS patients is statistically significant lower that those detected in NIND patients (P = 0.0254) and in HS1 (P = 0.001), whereas no significant was the different prevalence detected in MS and OIND patients (P>0.05).** The prevalence of SV40 antibodies in OIND patients is statistically significant lower that those detected in HS2 (P = 0.0403). The different prevalence of SV40 antibodies between the cohorts of NIND patients was not significant compared with the HS2 (P>0.05). Statistical analysis was performed using the χ2 test.Prevalence of immunoglobulin G antibodies reacting with Simian Virus 40 (SV40) viral protein (VP) mimotopes in serum samples of patients affected by MS, OIND, NIND and HS∧.