The incidence and influencing factors of HIV/AIDS-associated mental disorders.

Objective To investigate the incidence and influencing factors of mental disorders in people living with HIV/AIDS. And provide reference for clinical prevention of HIV associated mental disorder.Methods People living with HIV/AIDS admitted to our hospital from May 2017 to March 2023 were stratified randomly selected. Review the first hospitalization records and laboratory test data through the medical record management system then extracting relevant parameters as baseline data and followed up, Cox regression was used to analyze the influencing factors of HIV associated mental disorder.Results A total of 503 people living with HIV/AIDS meeting the study criteria were included, 71 patients diagnosed with mental disorder during follow-up, with a incidence of 14.1%. Multivariate analysis showed poor sleep (HR=3.813, 95%CI: 2.237~6.501), ART side effects (HR=1.740, 95%CI: 1.047~2.891), poor insight (HR=7.213, 95%CI: 4.277~12.163), abnormal CD4/CD8 cell ratio (HR=2.772, 95%CI: 1.246~6.163) and abnormal creatine kinase (HR=1.765, 95%CI: 1.086~2.871) were risk factors for HIV associated mental disorder.Conclusions People living with HIV/AIDS have a relatively high incidence of mental disorders within the first year of diagnosis, the influencing factors should be identified as early as possible when HIV/AIDS patients are diagnosed, and corresponding intervention plans should be formulated to prevent the occurrence and development of HIV associated mental disorder.