COMPARISON OF TERNARY CRYSTAL COMPLEXES OF HUMAN DIHYDROFOLATE REDUCTASE WITH NADPH AND A CLASSICAL ANTITUMOR FUROPYRIMDINE
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COMPARISON OF TERNARY CRYSTAL COMPLEXES OF HUMAN DIHYDROFOLATE REDUCTASE WITH NADPH AND A CLASSICAL ANTITUMOR FUROPYRIMDINE Descriptor: DIHYDROFOLATE REDUCTASE, N-[4-[(2,4-DIAMINOFURO[2,3D]PYRIMIDIN-5-YL)METHYL]METHYLAMINO]-BENZOYL]-L-GLUTAMATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Cody, V, Galitsky, N, Luft, J.R, Pangborn, W, Blakley, R.L, Gangjee, A. Deposit date: 1997-11-04 Release date: 1998-01-28 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Comparison of ternary crystal complexes of F31 variants of human dihydrofolate reductase with NADPH and a classical antitumor furopyrimidine. Anti-Cancer Drug Des., 13, 1998
人二氢叶酸还原酶与烟酰胺腺嘌呤二核苷酸磷酸（NADPH，dihydro-nicotinamide-adenine-dinucleotide phosphate）及经典抗肿瘤呋喃并嘧啶的三元晶体复合物比较
描述项：二氢叶酸还原酶（dihydrofolate reductase）、N-[4-[(2,4-二氨基呋喃并[2,3-d]嘧啶-5-基)甲基]甲氨基]苯甲酰基-L-谷氨酸、烟酰胺腺嘌呤二核苷酸磷酸（NADPH，dihydro-nicotinamide-adenine-dinucleotide phosphate）
作者：Cody V、Galitsky N、Luft J.R.、Pangborn W、Blakley R.L.、Gangjee A.
提交日期：1997-11-04
发布日期：1998-01-28
最后修改日期：2024-02-07
实验方法：X射线衍射（2.1 Å）
引用文献：《人二氢叶酸还原酶F31突变体与烟酰胺腺嘌呤二核苷酸磷酸（NADPH）及经典抗肿瘤呋喃并嘧啶类化合物的三元晶体复合物比较》，《抗癌药物设计》（Anti-Cancer Drug Des.），第13卷，1998年
创建时间：
1997-11-04
