five

Investigation of CL26 binding on AGPAT4 protein

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NIAID Data Ecosystem2026-05-02 收录
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https://www.omicsdi.org/dataset/pride/PXD057674
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We have identified CL26 as a covalent inhibitor against AGPAT4, an aberrant protein complicated in hepatocellular carcinoma (HCC). CL26 treatment reversed HCC stemness and resistance to the first-line medication sorafenib. This experiment was conducted to investigate the covalent binding of CL26 onto AGPAT4 in vitro.
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2025-07-21
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